Risk factors for recurrence in patients with cerebral infarction and the role of secondary prevention compliance

Objective To investigate the risk factors for recurrence of cerebral infarction and the role of secondary prevention compliance.Methods Two hundred sixty-nine patients with cerebral infarction were completed the follow-up study for 1 year after onset.The data such as basic information (including sex,age,and body weight index) ,modified Rankin scale (mRS) score,Essen stroke risk scale (ESRS) score (histories of hypertension,diabetes,heart disease,and smoking) ,and present prophylactic treatment ( oral anti-platelet aggregation drugs,antihypertensive drugs,hypoglycemic agents,lipid-lowering drugs,and salt restriction) were collected.The patients were divided into a recurrent group (n = 73) and a non-recurrence of group (n = 196) according to whether they had recurrence or not within 1 year.The possible risk factors for recurrence of cerebral infarction and the role of all risk factors for secondary prevention compliance were analyzed.Results ①The proportions of hypertension,diabetes,hyperlipidemia and smoking in the recurrent group was higher than those in the non-recurrent group.The differences were statistically significant (allP0.01).②A multiple logistic regression analysis showed that the risk factors for recurrent cerebral infarction included hypertension,diabetes,smoking,and hyperlipidemia.③The recurrence rate (24.42% ) in patients who took aspirin was lower than that did not (38.46% ) (χ~2 =4.181, P 0.05).④ According to the calculation of the numbers of patients with the histories of hypertension,di- abetes,hyperlipidemia,and smoking,the recurrence rate in those who took appropriate secondary prevention interventions was lower than those who did not.The differences were statistically significant (all P 0.05).Conclusion The recurrent risk factors of recurrence in patients with cerebral infarction include hypertension,diabetes,smoking,and hyperlipidemia.The favorable secondary prevention compliance is helpful to reduce the recurrence rate of cerebral infarction.