Experimental Observation of G Banding Verifying X-ray Workers' Chromosome Translocation Detected by FISH.

Objective FISH is the most effective way of detecting chromosome aberration and many factors affect its accuracy.G-banding is used to verify the results of early X-ray workers'chromosome translocation examined by FISH.Methods The chromosome translocations of early X-ray workers have been analysed by FISH(fluorescence in situ hybridization)and G-banding,yields of translocation treated with statistics.Results The chromosome aberrations frequencies by tow methods are closely related.Conclusion FISH is a feasible way to analyse chromosome aberrations of X-ray workers and reconstruct dose.