2009•Hereditas (Beijing)Requires access

Progresses on the methods of tumor chromosome aberration analysis

Yuanbo Xue

Abstract

Most cancers are known to be associated with chromosome aberration, and chromosome analysis is essential to understand the relationships between chromosome aberration and cancer. Here we briefly introduce several methods of chromosome aberration detection, including G-banding, fluorescence in situ hybridization (FISH), spectral karyotyping (SKY), multi-fluorescence in situ hybridization (M-FISH), cross-species color banding (Rx-FISH), comparative genomic hybridization (CGH)and Array comparative genomic hybridization (Array CGH).

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Available abstract

Key concepts: Comparative genomic hybridization, Fluorescence in situ hybridization, Karyotype, Chromosome aberration, Chromosome, Biology, Fish <Actinopterygii>, Genetics