2008•Medical Journal of West ChinaRequires access
Cost-effectiveness analysis of sequential therapy of levofloxacin for the elder's lower respiratory tract infection
Daishun Liu
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Abstract
Objective To evaluate clinical therapeutic and economic effects of sequential therapy of levofloxacin for the elder's lower respiratory tract infection.Methods 80 cases of lower respiratory tract infection were randomly divided into two groups,40 cases in sequential group were treated with IV injection of levofloxacin 400mg/d for 4-5 days,then took levoflocacin capsules 400mg/d for 5-9days;40 cases in control group were treated with IV injection of levofloxacin 400mg/d for 7-14 days.Cost-effectiveness analysis was made after ending effect between the treatment.Results By statistical comparison,the therapeutic effect between the two group was similar,but cost-effectiveness ratio in sequential group was lower than that in control group(P0.001).Conclusion The sequential therapy of levofloxacin for the elder's lower respiratory tract infection is safe and effective;moreover,the cost-effectiveness ratio of sequential group is more reasonable than that of control group.