Catalytic Synthesis of O-methyl-phenoxyacetic Acid with Cetyltrimethylammonium Bromide as Catalyst

O-methyl-phenoxyacetic acid was synthesized applied cetyltrimethylammonium bromide as catalyst.Cetyltrimethylammonium bromide had higher catalytic activity,could be accelerate the synthesis of o-methyl-phenoxyacetic acid.Effect of molar ratio of 2-methyl-phenol to chloroacetic acid,catalyst amount,reaction time and reaction temperature on yield,and the performance of the repeated use of catalyst,were studied.The best reaction conditions were as followed:85℃,molar ratio of 2-methyl-phenol to chloroacetate 1:5,catalyst weight of 0.3 g,reaction time was 3.5h.This reaction yield was 47.07%.