2010•Technology & Development of Chemical IndustryRequires access
Cetyltrimethylammonium Bromide Catalytic Synthesis of 4-Methyl-phenoxyacetic Acid
Huang Suo-yi
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Abstract
Applied cetyltrimethylammonium bromide as catalyst,4-methyl-phenoxyacetic acid was synthesized with chloroacetate and 4-methyl phenol.Cetyltrimethylammonium bromide had higher catalytic activity and could be accelerate the synthesis of 4-methyl-phenoxyacetic acid.Molar ratio of 4-methyl phenol to chloroacetic acid,catalyst amount,reaction time and reaction temperature on yield and performance of the repeated use of catalyst was studied.The best reaction conditions were as followed: under 80℃,molar ratio of 4-methyl phenol to chloroacetate 1:2,catalyst weight of 0.2 g,reaction time was 2.5h.This yield of 4-methyl-phenoxyacetic acid was 51.93%.