2005•The Practical Journal of CancerRequires access

Expression of Bcl-2、Bax protein in Human Uterine Leiomyoma

Tan Bu-zhe

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Abstract

Objective The purpose of this thesis is to investigate the relation between Bcl-2、Bax and the occurance of human uterine leiomyoma.Methods The expression of Bcl-2、Bax protein was employed to examine immunohistochemically in leiomyoma of the experiment group and adjacent normal myometrium of controling group.Results The expression of Bcl-2 protein in human uterine was 85% was significantly higher than that of adjacent nomal myometrium 27%.while the expressions of Bax protein was evidently lower in the former 17% that of latter 75% in contrast.Conclusion The developping of human uterine leiomyoma was related to the expression of Bcl-2、the loss expression of Bax.

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What this paper is about

Objective The purpose of this thesis is to investigate the relation between Bcl-2、Bax and the occurance of human uterine leiomyoma.Methods The expression of Bcl-2、Bax protein was employed to examine immunohistochemically in leiomyoma of the experiment group and adjacent normal myometrium of controling group.Results The expression of Bcl-2 protein in human uterine was 85% was significantly higher than that of adjacent nomal myometrium 27%.while the expressions of Bax protein was evidently lower in the former 17% that of latter 75% in contrast.Conclusion The developping of human uterine leiomyoma was related to the expression of Bcl-2、the loss expression of Bax.

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Available abstract

Objective The purpose of this thesis is to investigate the relation between Bcl-2、Bax and the occurance of human uterine leiomyoma.Methods The expression of Bcl-2、Bax protein was employed to examine immunohistochemically in leiomyoma of the experiment group and adjacent normal myometrium of controling group.Results The expression of Bcl-2 protein in human uterine was 85% was significantly higher than that of adjacent nomal myometrium 27%.while the expressions of Bax protein was evidently lower in the former 17% that of latter 75% in contrast.Conclusion The developping of human uterine leiomyoma was related to the expression of Bcl-2、the loss expression of Bax.

Key concepts: Myometrium, Uterine leiomyoma, Leiomyoma, Protein expression, Immunohistochemistry, BAX Protein, Andrology, Biology

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