Analysis of Drug Resistance and Clinical Distribution of 276 Isolates of Enterococci

Objective To analyze the distribution and the changes of drug resistance of isolated Enterococcus.To supply reliable basement for rational application of antibiotics in clinic.Methods We had collected 276 isolates of Enterococcus by cultured in normal method from January 2007 to December 2009.It was conducted with Microscan microbiology analysis system to identify Enterococcus and to analyse the characteristics of species distribution,the condition of drug-resistance,drug-resistance of high concentration aminoglycoside antibiotics and β-lactamase detected result.Results There were 276 strains Enterococcus.Among them,Enterococcus faecalis were 139 strains,E.faecium were 121 strains,the others were 16 strains.Drug-resistant of Enterococcus faecium was higher than that of Enterococcus faecalis.They had higher resistance to Tetracycline such as Erythromycin,Ciprofloxacin and Rifampin,they also had highly sensitive to Vancomycin and Linezolid.Conclusion The infection in many system were mainly caused by Enterococcus faecalis and Enterococcus faecium with multidrug resistance.Hospital administers should strengthen the management of antibiotics usage so as to decrease drug-resistance of enterococcus.