2012•Chinese Journal of New Drugs and Clinical RemediesRequires access

Effects of N-acetyl-seryl-aspartyl-lysyl-proline on myofibroblasts differentiation in lung of rats with silicosis

Fang Yang

Abstract

AIM To investigate the role of AcSDKP in regulating myofibroblast differentiation in the lung of rats with silicosis.METHODS SiO2 powders(50 g.L-1) were douched in bronchial tube of rat to make the silicotic model.Sixty Wistar rats were randomly divided into normal control 4 weeks group and 8 weeks group,model 4 weeks group and 8 weeks group,AcSDKP treatment group(AcSDKP 800 μg.kg-1.d-1 after modeling

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Silicosis, Myofibroblast, Lung fibrosis, Lung, Medicine, Internal medicine, Pulmonary fibrosis, Endocrinology