Application of time-intensity curve of contrast-enhanced ultrasonography in the diagnosis of breast masses

Objective To discuss the diagnostic value of time-intensity curve analysis of contrast-enhanced ultrasonography(CEUS) in the diagnosis of breast masses. Methods Totally, 49 patients with breast masses (22 benign, 27 malignant) were examined with CEUS . SonoVue was used as a contrast media. The dynamic CEUS images were analyzed with the time-intensity curve software. Results After contrast agent injection, high enhancement cases in malignant group were more than those in benign group. The correlation between benign and malignant lesions was stastically significant(P0.05). There was statistical difference between breast benign and malignant tumors in configuration and parameters on time-intensity curve. The arrival time and the time to peak enhancement were shorter in malignant group than those in benign group(P0.05). The slope of the rising part and peak intensity was greater in malignant group than that in benign group(P0.05). Conlusion Time-intensity curve analysis of contrast-enhanced ultrasonography is helpful in differentiating diagnosis of breast masses.