2012Chinese Journal of Clinical PharmacyRequires access

Comparison of the effect of dezocine and tramadol on shivering after epidural anesthesia for cesarean section

Zhou Bin-fu

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Abstract

AIM To compare the effect of dezocine with tramadol on shivering after epidural anesthesia for cesarean section.METHODS Sixty lying-in-women with ASAⅠwith shivering appearing after epidural anesthesia were randomly divided into 2 groups,and given intravenous injection of dezocine 0.1 mg·kg~(-1)(group D,n = 30) or tramadol 1 mg·kg~(-1)(group Q,n = 30),respectively after delivery of the fetus.All patients were monitored by ECG,BP,MAP and SpO_2.The shivering treatment effect after medication of 7.5 min,15 min and the chills recurrence rate within 30 min were recorded.The adverse drug reactions(nausea and vomiting,dizziness,sleepiness,respiratory depression and chest tightness) were also recorded.RESULTS The 2 groups had no significant difference(P0.05).The incidence of nausea and vomiting in group D was lower than that in group Q(P0.05),and the incidence of dizziness and sleepiness in group D was higher than that in group Q(P0.05).CONCLUSION Dezocine and tramadol can provide good efficacy in treatment of shivering during epidural cesarean section.However,the incidence of nausea and vomiting in the dezocine group is significantly lower than in the tramadol group.

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AIM To compare the effect of dezocine with tramadol on shivering after epidural anesthesia for cesarean section.METHODS Sixty lying-in-women with ASAⅠwith shivering appearing after epidural anesthesia were randomly divided into 2 groups,and given intravenous injection of dezocine 0.1 mg·kg~(-1)(group D,n = 30) or tramadol 1 mg·kg~(-1)(group Q,n = 30),respectively after delivery of the fetus.All patients were monitored by ECG,BP,MAP and SpO_2.The shivering treatment effect after medication of 7.5 min,15 min and the chills recurrence rate within 30 min were recorded.The adverse drug reactions(nausea and vomiting,dizziness,sleepiness,respiratory depression and chest tightness) were also recorded.RESULTS The 2 groups had no significant difference(P0.05).The incidence of nausea and vomiting in group D was lower than that in group Q(P0.05),and the incidence of dizziness and sleepiness in group D was higher than that in group Q(P0.05).CONCLUSION Dezocine and tramadol can provide good efficacy in treatment of shivering during epidural cesarean section.However,the incidence of nausea and vomiting in the dezocine group is significantly lower than in the tramadol group.

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Available abstract

AIM To compare the effect of dezocine with tramadol on shivering after epidural anesthesia for cesarean section.METHODS Sixty lying-in-women with ASAⅠwith shivering appearing after epidural anesthesia were randomly divided into 2 groups,and given intravenous injection of dezocine 0.1 mg·kg~(-1)(group D,n = 30) or tramadol 1 mg·kg~(-1)(group Q,n = 30),respectively after delivery of the fetus.All patients were monitored by ECG,BP,MAP and SpO_2.The shivering treatment effect after medication of 7.5 min,15 min and the chills recurrence rate within 30 min were recorded.The adverse drug reactions(nausea and vomiting,dizziness,sleepiness,respiratory depression and chest tightness) were also recorded.RESULTS The 2 groups had no significant difference(P0.05).The incidence of nausea and vomiting in group D was lower than that in group Q(P0.05),and the incidence of dizziness and sleepiness in group D was higher than that in group Q(P0.05).CONCLUSION Dezocine and tramadol can provide good efficacy in treatment of shivering during epidural cesarean section.However,the incidence of nausea and vomiting in the dezocine group is significantly lower than in the tramadol group.

Key concepts: Shivering, Tramadol, Anesthesia, Nausea, Vomiting, Medicine, Dezocine, Incidence (geometry)

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