ScholarLens Back to search
2009•Journal of Tongji UniversityRequires access

Th17 type cytokines in patients with rheumatoid arthritis and its significance to clinic

Zhou Jie-ru

Open publisher page 0 citations

Abstract

Objective To investigate IL-6,IL-17 levels in blood and synovial fluid of patients with rheumatoid arthritis,their variable features in arthritis duration and relationship to laboratory markers.Methods IL-6、IL-17 levels from RA patients and controls were evaluated by enzyme-linked immunoassay(ELISA).Results Serum IL-6,IL-17 values were higher in RA patients compared with those in the controls,and so were in RA synovial fluid.There was a positive correlation between IL-16 and CRP,ESR,RF.Conclusion Th17 type cytokines overexpresses in serum and synovial fluid of RA patients,and Th17 type cytokine may play an important role in the pathogenesis of RA.

About this research paper

What this paper is about

Objective To investigate IL-6,IL-17 levels in blood and synovial fluid of patients with rheumatoid arthritis,their variable features in arthritis duration and relationship to laboratory markers.Methods IL-6、IL-17 levels from RA patients and controls were evaluated by enzyme-linked immunoassay(ELISA).Results Serum IL-6,IL-17 values were higher in RA patients compared with those in the controls,and so were in RA synovial fluid.There was a positive correlation between IL-16 and CRP,ESR,RF.Conclusion Th17 type cytokines overexpresses in serum and synovial fluid of RA patients,and Th17 type cytokine may play an important role in the pathogenesis of RA.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate IL-6,IL-17 levels in blood and synovial fluid of patients with rheumatoid arthritis,their variable features in arthritis duration and relationship to laboratory markers.Methods IL-6、IL-17 levels from RA patients and controls were evaluated by enzyme-linked immunoassay(ELISA).Results Serum IL-6,IL-17 values were higher in RA patients compared with those in the controls,and so were in RA synovial fluid.There was a positive correlation between IL-16 and CRP,ESR,RF.Conclusion Th17 type cytokines overexpresses in serum and synovial fluid of RA patients,and Th17 type cytokine may play an important role in the pathogenesis of RA.

Key concepts: Rheumatoid arthritis, Synovial fluid, Medicine, Pathogenesis, Cytokine, Immunology, Arthritis, Immunoassay

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Th17 type cytokines in patients with rheumatoid arthritis and its significance to clinic — Research Paper | ScholarLens