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2007•Chinese Journal of Difficult and Complicated CasesRequires access

Relationship between von Willebrand factor and coronary artery lesion in patients with coronary heart disease

Shuren Li

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Abstract

Objective To investigate the relationship between von Willebrand factor(vWF)and coronary artery angion in patients with coronary heart disease(CHD).Methods The vWF was detected and coronary angiography were performed in 52 patients with CHD and 16 healthy subjects.CHD patients were divided into 3 groups(type A,B and C)based on the coronary artery lesions.Results The levels of vWF in CHD group were significantly higher than those of control group [(162±44)% vs(89±16)%,P0.01].The levels of vWF were positively correlated with the severity of coronary lesions(r=0.452,P0.01).The plasma vWF levels in group C were significantly higher than those of group B [(194±37)% vs(160±39)%),P0.01],but which in group B were obviously higher than those in group A [(160±39)% vs(132±31)%,P0.01].Conclusion The levels of plasma vWF are closelyrelated with the severity of coronary artery lesion in CHD patients.

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What this paper is about

Objective To investigate the relationship between von Willebrand factor(vWF)and coronary artery angion in patients with coronary heart disease(CHD).Methods The vWF was detected and coronary angiography were performed in 52 patients with CHD and 16 healthy subjects.CHD patients were divided into 3 groups(type A,B and C)based on the coronary artery lesions.Results The levels of vWF in CHD group were significantly higher than those of control group [(162±44)% vs(89±16)%,P0.01].The levels of vWF were positively correlated with the severity of coronary lesions(r=0.452,P0.01).The plasma vWF levels in group C were significantly higher than those of group B [(194±37)% vs(160±39)%),P0.01],but which in group B were obviously higher than those in group A [(160±39)% vs(132±31)%,P0.01].Conclusion The levels of plasma vWF are closelyrelated with the severity of coronary artery lesion in CHD patients.

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Available abstract

Objective To investigate the relationship between von Willebrand factor(vWF)and coronary artery angion in patients with coronary heart disease(CHD).Methods The vWF was detected and coronary angiography were performed in 52 patients with CHD and 16 healthy subjects.CHD patients were divided into 3 groups(type A,B and C)based on the coronary artery lesions.Results The levels of vWF in CHD group were significantly higher than those of control group [(162±44)% vs(89±16)%,P0.01].The levels of vWF were positively correlated with the severity of coronary lesions(r=0.452,P0.01).The plasma vWF levels in group C were significantly higher than those of group B [(194±37)% vs(160±39)%),P0.01],but which in group B were obviously higher than those in group A [(160±39)% vs(132±31)%,P0.01].Conclusion The levels of plasma vWF are closelyrelated with the severity of coronary artery lesion in CHD patients.

Key concepts: Medicine, Internal medicine, Von Willebrand factor, Cardiology, Artery, Coronary angiography, Coronary artery disease, Lesion

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Relationship between von Willebrand factor and coronary artery lesion in patients with coronary heart disease — Research Paper | ScholarLens