2007Journal of Dalian UniversityRequires access

Effect of Simvastatin on Treating Dyslipidemia of Type 2 Diabetes with Different Dosage

Xiao-jing Yu

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Abstract

Objective:To observe the therapeutic effect of different dosage of simvastatin in the treatment of patients with dyslipidemia of type 2 diabetes.Methods:104 patients with different clinical symptom,blood glucose and blood lipid were entered the study and randomized to three groups:80 mg group,40 mg group and 20 mg group by dosage of simvastatin.Lipid levels were detected after 24 weeks.Result:Levels of LDL-C and TC reduced significantly in 80 mg-group,40 mg-group and 20 mg-group.While the effect of 80 mg group was better than that of other groups.Conclusion:Intensification therapeutic dosage of simvastatin was better than common prescription dosage in treating dyslipidemia of type 2 diabetes.

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What this paper is about

Objective:To observe the therapeutic effect of different dosage of simvastatin in the treatment of patients with dyslipidemia of type 2 diabetes.Methods:104 patients with different clinical symptom,blood glucose and blood lipid were entered the study and randomized to three groups:80 mg group,40 mg group and 20 mg group by dosage of simvastatin.Lipid levels were detected after 24 weeks.Result:Levels of LDL-C and TC reduced significantly in 80 mg-group,40 mg-group and 20 mg-group.While the effect of 80 mg group was better than that of other groups.Conclusion:Intensification therapeutic dosage of simvastatin was better than common prescription dosage in treating dyslipidemia of type 2 diabetes.

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Available abstract

Objective:To observe the therapeutic effect of different dosage of simvastatin in the treatment of patients with dyslipidemia of type 2 diabetes.Methods:104 patients with different clinical symptom,blood glucose and blood lipid were entered the study and randomized to three groups:80 mg group,40 mg group and 20 mg group by dosage of simvastatin.Lipid levels were detected after 24 weeks.Result:Levels of LDL-C and TC reduced significantly in 80 mg-group,40 mg-group and 20 mg-group.While the effect of 80 mg group was better than that of other groups.Conclusion:Intensification therapeutic dosage of simvastatin was better than common prescription dosage in treating dyslipidemia of type 2 diabetes.

Key concepts: Simvastatin, Dyslipidemia, Medicine, Type 2 diabetes, Therapeutic effect, Blood lipids, Internal medicine, Diabetes mellitus

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