Study on comparison of therapeutic efficacy of high flux hemodialysis with conventional hemodialysis in treatment of patients with chronic uremia

Objective To compare the therapeutic efficacy of high flux hemodialysis with conventional hemodialysis in treatment of patients with chronic uremia. Methods A total of 82 cases of chronic uremia were randomly divided into observation group( n = 41) and control group( n = 41),and patients in former group received high flux hemodialysis,while patients in latter group were given with conventional hemodialysis. Results ① Before and after treatment,the rate of decrease in serum intact-parathyroid hormone( iPTH),β2-microglobulin( β2-M)and phosphorus( P) in observation group was significantly higher than that of control group( P 0. 05). There was no significant difference in rate of decrease in blood urea nitrogen( BUN) and creatinine( Cr) between observation group and control group. ②The incidence of adverse reactions in observation group was significantly lower than that of control group( P 0. 05). Conclusion In comparison with conventional hemodialysis,high flux hemodialysis in treatment of patients with chronic uremia shows better therapeutic efficacy in reducing macromolecules and lower incidence of adverse reactions.