Clinical analysis of platelet parameters in patients with hepatitis B cirrhosis

Objective To observe relationship of the changes of platelet parameters with f hepatic cirrhosis,and to investigate its clinical significance.Methods 114 cases of patients with hepatitis B cirrhosis were divided into complicated with upper gastrointestinal bleeding group(54 cases),no gastrointestinal bleeding group(60 cases),another 50 healthy persons were as control group,platelet parameters(PLT,PDW,PCT,MPV) the two groups were compared.Results Compared with the control group,PLT and PCT in patients with hepatic cirrhosis were(71.95±55.35)×109/L,0.08%±0.07%,these were significantly reduced(P0.01).MPV,PDW were(12.06±1.23)fL,15.92%±3.33%,these increased significantly(P0.01).PLT,PCT,MPV,PDW of hepatic cirrhosis complicated by hemorrhage of digestive tract group decreased significantly compared with no gastrointestinal bleeding group(P0.05).Conclusion Determination of the platelet parameters in patients with liver cirrhosis can has important guiding significance in liver function damage assessment and judgement of bleeding tendency.