Assessment of left ventricular systolic function in patients with dilated cardiomyopathy by automated motion tracking of mitral annular displacement

Objective To explore the clinical value of automated motion tracking of mitral annular displacement for assessing left ventricular systolic function in patients with dilated cardiomyopathy(DCM). Methods Left ventricular end-diastolic dimension(LVEDd),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV)and left ventricular ejection fraction(LVEF)were measured with two-dimensional echocardiography in 30 patients with DCM and 20 healthy controls.The maximal displacement of six points of mitral annulus(Ds)was measured with TMAD,and the correlation between mean displacement(MDs)and LVEF was analyzed. Results Compared with healthy controls,LVEDd,LVEDV,LVESV increased significantly in DCM patients(P0.001),and LVEF decreased significantly(P0.001).The displacement of six points of mitral annulus was lower in DCM patients than those in healthy controls(P0.001).TMAD was positively correlated with Simpson’s LVEF in healthy controls and DCM patients(r=0.878,0.687,P0.001). Conclusion TMAD can assess the left ventricular systolic function in patients with DCM,and it could be a new method for clinically evaluating the left ventricular systolic function.