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2011•Journal of Brain and Nervous DiseasesRequires access

Clinical misdiagnosis analysis of neurosyphilis(with 1 cases report)

Mei Yong-xia

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Abstract

Objective To investigate the clinical features and diagnostic methods and the causes of delayed diagnosis of neurosyphilis in new age.Methods We reported one case with neurosyphilis.The clinical features of neurosyphilis were analyzed.In the new age,the neurosyphilis was easy to make delayed diagnosis because its concealed.Results Patients' ages were mainly midage.Cognitive disordes and mental disorders and epileptic seizure were main clinical manifestations.All patients's Treponema pallidum particle assay(TPPA) were positive.Brain MRI had no characteristic change.General paresis of insane could be cure and the MOCA score could be up.Conclusions Because of the complex clinical manifestations,the rate of misdiagnose is high.TPPA should be detected as a routine item.General paresis of insane could be cure.

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Objective To investigate the clinical features and diagnostic methods and the causes of delayed diagnosis of neurosyphilis in new age.Methods We reported one case with neurosyphilis.The clinical features of neurosyphilis were analyzed.In the new age,the neurosyphilis was easy to make delayed diagnosis because its concealed.Results Patients' ages were mainly midage.Cognitive disordes and mental disorders and epileptic seizure were main clinical manifestations.All patients's Treponema pallidum particle assay(TPPA) were positive.Brain MRI had no characteristic change.General paresis of insane could be cure and the MOCA score could be up.Conclusions Because of the complex clinical manifestations,the rate of misdiagnose is high.TPPA should be detected as a routine item.General paresis of insane could be cure.

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Available abstract

Objective To investigate the clinical features and diagnostic methods and the causes of delayed diagnosis of neurosyphilis in new age.Methods We reported one case with neurosyphilis.The clinical features of neurosyphilis were analyzed.In the new age,the neurosyphilis was easy to make delayed diagnosis because its concealed.Results Patients' ages were mainly midage.Cognitive disordes and mental disorders and epileptic seizure were main clinical manifestations.All patients's Treponema pallidum particle assay(TPPA) were positive.Brain MRI had no characteristic change.General paresis of insane could be cure and the MOCA score could be up.Conclusions Because of the complex clinical manifestations,the rate of misdiagnose is high.TPPA should be detected as a routine item.General paresis of insane could be cure.

Key concepts: Neurosyphilis, Paresis, Medicine, Syphilis, Pediatrics, Clinical diagnosis, Surgery, Immunology

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