Pathogens and Drug Resistance Observed in Elderly Patients with Lower Respiratory Tract Infections

Objective To provide an objective basis for clinical medication by monitoring and analyzing the distribution of pathogenic bacteria and drug resistance in elderly patients with lower respiratory tract infections in our hospital.Methods Sputum from elderly patients with lower respiratory tract infections in our surgical treatment from January 2010 to January 2012 was collected.Through strain identification and susceptibility testing,the common pathogenic bacteria strains and sensitive drugs of last two years were observed and analyzed.Results ①There was 229 strains of Gram-positive cocci,accounting for 17.9%;894 strains of Gram-negative bacilli,accounted for 69.9%.A total of 196 strains of Klebsiella pneumoniae were detected,accounted for 15.4%;167 strains of Escherichia coli for 13.1%;152 strains of Staphylococcus aureus lactis for 11.9%;P186 strains of seudomonas aeruginosa for 14.6%;162 strains of Fungi for 12.6%.②Common gram-negative bacilli more serious resistance to cefazolin,ampicillin and other drugs;The lowest resistance rate was to imipenem;Staphylococcus aureus is the most sensitive to vancomycin,no apparent resistance,other drugs have varying degrees of resistance.Conclusion In the clinical treatment of lower respiratory tract infections in elderly patients,the drugs which were sensitive to the anti-Gram-negative bacilli should be first considered;if sputum cultures perform gram-positive bacterias,the preferred vancomycin drugs should firstly be considered.