Antimicrobial resistance of 168 isolates of pseudomonas aeruginosa causing nosocomial infection

OBJECTIVE To investigate the antimicrobial resistance of Pseudomonas aeruginosa(PAE) causing nosocomial infection and provide the scientific evidence for clinically reasonable use of antibiotics.METHODS Referring to National Guide to Clinical Laboratory Procedures,the bacterial culture and identification were performed by the rountine methods.The susceptibility testing was performed by K-B methods recommended by CLSI.RESULTS Among 168 isolates of PAE,PAE was 100.0% sensitive to imipenem and meropenem.The resistance rates to cefoperazone/sulbactam,piperacillin/tazobactam and amikacin were the lower,varying form 10.1% to 14.3%.The resistance rate of sulfamethoxazole/trimethoprim(58.3%) was the highest.The antibiotics with above 30.0% resistance rate were cefotaxime,ciprofloxacin,gentamicin and aztreonam.CONCLUSION The serious antimicrobial resistance of PAE has been occurred in grass-root hospitals.It should strengthen the monitoring and controlling of bacterial drug resistance.