~(18)F-FDG PET/CT imaging in the diagnosis of postoperative of gastric cancer recurrence and metastasis

Objective:To assess the value of 18F-fluorodeoxyglucose positron emission and computed tomography(18F-FDG PET/CT) in the post-operative patients with gastric cancer recurrence and metastasis.Methods:Of all the 112 patients who had received PET/CT examination for 150 times,the image analysis using visual and semi-quantitative analysis(SUVave),lesions confirmed according to the results of pathological examination,a variety of imaging techniques and clinical follow-up examination,follow-up time for more than half a year.Results:Sixteen cases showed tumor recurrence and metastasis,PET/CT diagnosis of gastric remnant recurrence sensitivity was 81.2%,specificity was 100%,accuracy was 97.3%.SUVave of recurrent lesions was 4.4±1.2,SUVave of anastomotic inflammatory lesions was 2.6±0.5,difference was statistically significant(t=3.9370,P =0.0005).PET/CT diagnosis of gastric cancer metastasis:sensitivity was 94.1%,specificity was 96.7% and accuracy was 95.5%.Twenty-six cases who had received PET/CT examination for two or more than two times,15 cases who received the first PET/CT examination and 6 cases showed improvement after radiotherapy and chemotherapy.These patients survived after 6 months to 2 years of follow-up;PET imaging in 9 cases after treatment showed no significant change in conditions or the emergence of new lesions,the patient survival time was 3 months to 1 year.Conclusions:18F-FDG PET/CT in the postoperative recurrence and metastasis of gastric cancer have a good diagnostic value,and have certain value in monitoring postoperative chemotherapy of gastric cancer.