2019•Int J Radiat Med Nucl MedRequires access

18 F-FDG PET/CT在胃癌复发及转移监测中的临床价值

徐鑫, 邓胜明, 李继会, 黄莹, Wei Zhang

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Abstract

Objective To investigate the value of 18F-FDG PET/CT in the detection of gastric cancer recurrence and metastasis. Methods A retrospective analysis involving 52 patients with suspected recurrence and metastasis after gastric cancer surgery and who underwent 18F-FDG PET/CT and contrast-enhanced CT examinations over the period of January 2013 to August 2017 was performed, including 40 males and 12 females, aged between 30 and 86 years old(61.73±11.44). Receiver operating characteristic analysis was conducted on the basis of imaging data for the detection of a cutoff SUVmax value that is indicative of the presence of recurrent lesions. Differences among groups were determined through the t-test. The results of different methods were compared through the χ2 test. Results The specificity of 18F-FDG PET/CT was favorable and was higher than that of the qualitative analytical method(χ2=5.439, P 0.05). Conclusions The performance of PET/CT in the diagnosis of gastric cancer recurrence and metastasis is better than that of contrast-enhanced CT. Therefore, 18F-FDG PET/CT imaging has a high clinical value in the postoperative detection of gastric cancer. Key words: Stomach neoplasms; Fluorodeoxyglucose F18; Positron emission tomography computed tomography; Recurrence; Postoperative; Contrast-enhanced computed tomography

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Objective To investigate the value of 18F-FDG PET/CT in the detection of gastric cancer recurrence and metastasis. Methods A retrospective analysis involving 52 patients with suspected recurrence and metastasis after gastric cancer surgery and who underwent 18F-FDG PET/CT and contrast-enhanced CT examinations over the period of January 2013 to August 2017 was performed, including 40 males and 12 females, aged between 30 and 86 years old(61.73±11.44). Receiver operating characteristic analysis was conducted on the basis of imaging data for the detection of a cutoff SUVmax value that is indicative of the presence of recurrent lesions. Differences among groups were determined through the t-test. The results of different methods were compared through the χ2 test. Results The specificity of 18F-FDG PET/CT was favorable and was higher than that of the qualitative analytical method(χ2=5.439, P 0.05). Conclusions The performance of PET/CT in the diagnosis of gastric cancer recurrence and metastasis is better than that of contrast-enhanced CT. Therefore, 18F-FDG PET/CT imaging has a high clinical value in the postoperative detection of gastric cancer. Key words: Stomach neoplasms; Fluorodeoxyglucose F18; Positron emission tomography computed tomography; Recurrence; Postoperative; Contrast-enhanced computed tomography

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Available abstract

Objective To investigate the value of 18F-FDG PET/CT in the detection of gastric cancer recurrence and metastasis. Methods A retrospective analysis involving 52 patients with suspected recurrence and metastasis after gastric cancer surgery and who underwent 18F-FDG PET/CT and contrast-enhanced CT examinations over the period of January 2013 to August 2017 was performed, including 40 males and 12 females, aged between 30 and 86 years old(61.73±11.44). Receiver operating characteristic analysis was conducted on the basis of imaging data for the detection of a cutoff SUVmax value that is indicative of the presence of recurrent lesions. Differences among groups were determined through the t-test. The results of different methods were compared through the χ2 test. Results The specificity of 18F-FDG PET/CT was favorable and was higher than that of the qualitative analytical method(χ2=5.439, P 0.05). Conclusions The performance of PET/CT in the diagnosis of gastric cancer recurrence and metastasis is better than that of contrast-enhanced CT. Therefore, 18F-FDG PET/CT imaging has a high clinical value in the postoperative detection of gastric cancer. Key words: Stomach neoplasms; Fluorodeoxyglucose F18; Positron emission tomography computed tomography; Recurrence; Postoperative; Contrast-enhanced computed tomography

Key concepts: Medicine, Positron emission tomography, Metastasis, Nuclear medicine, Radiology, Cancer, Stomach cancer, Computed tomography

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18 F-FDG PET/CT在胃癌复发及转移监测中的临床价值 — Research Paper | ScholarLens