2003•Zhonghua laonian yixue zazhiRequires access
Study on the atherosclerosis of carotid and femoral arteries and the endothelial function in elderly diabetics
Yi Miao
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Abstract
Objective To investigate atherosclerosis of carotid and femoral arteries and the endothelial function in elderly diabetics. Methods The endothelium dependent relaxing function of blood vessels, intima media thickness (IMT) of carotid arteries, and the plaque in carotid and femoral arteries were measured using B mode ultrasound in 32 elderly diabetics, 35 elderly patients with both diabetics and coronary artery disease(CAD), and 30 controls. Results The flow mediated dilatation in the group with both diabetics and CAD(2 81±1 56)% was significantly lower than that in the single diabetic group(5 58±1 13)%, and both groups were significantly lower than that of the control group 〔(9 63± 1 81 )%, P 0 05〕. The IMT of common carotid arteries in the group with both diabetics and CAD (1 05±0 16 )mm was significantly higher than that of the diabetic group (0 92±0 13)mm, and IMT in both groups was significantly higher than that of the control group 〔(0 78±0 07) mm, P 0 05〕. The plaque index of carotid and femoral arteries in the two diabetic groups was significantly higher than that of the control group( P 0 05). Conclusions The endothelium dependent vasodilatation was impaired in elderly diabetics. The aged diabetics is of higher incidence of atherosclerosis of main arteries since the endothelium dependent relaxing function decreased.