Study on the Preparation of Chloramphenicol Molecular Imprinted Polymers by Precipitation Polymerizationn Water-containing Medium and Their Adsorption Characteristics

Precipitation polymerization was used to prepare molecular imprinted polymers(MIPs) of chloramphenicol.using chloramphenicol as template molecular,MAA as the functional monomer,ethylene glycol dimethacrylate as the cross-linker(chloramphenicol:MAA:ethylene glycol dimethacrylate was 1:4:20(mole ratio)),acetonitrilewater system as the porogenic solvent,and 2,2'-Azobisiso butyronitrile as the initiator,chloramphenicol molecular imprinted polymer microspheres with an average size of 13.83 μm were synthesized with water bathing at 60 ℃ and stirring at the speed of 400 r·min-1.The product showed a maximum adsorption of 85 μmol·g-1 for chloramphenicol.Linear equation was obtained by Scatchard analysis,which illustrated that there were homogeneous selectivity adsorption sites on the surface of MIPs and its maximum apparent adsorption was 529.42 μmol·g-1.