1997•Chinese Journal of PharmaceuticalsRequires access

DETERMINATION OF THYMOL IN CREAM BY SECOND ORDER DERIVATIVE SPECTROPHOTOMETRY

Zhang Xiang

Abstract

The second order derivative spectrophotometric method was established for the determination of thymol in cream.The amplitude D between 238 nm and 254 nm was linear with concentration of thymol within the range of 2.8～22.1 μg/ml.The average recovery of thymol was 99.29%, RSD was 0.35%.Its regression equation is D =7.9249 C + 0.001964 ( r =0.9999).The method is simple and accurate.

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Key concepts: Thymol, Chemistry, Derivative (finance), Chromatography, Spectrophotometry, Second derivative, Analytical Chemistry (journal), Mathematics