Study on Optimization of Extraction Process of Ursolic Acid from Potentilla discolor Bge with Ultrasonic
HU Mei-zhong
Abstract
HU Mei-zhong
Abstract
Objective: To screen optimum the extraction process of ursolic acid from Potentilla discolor Bge. Methods: ultrasonics extraction was used to extract. The optimum extraction process was confimed by the orthogonal test. The content of ursolic acid in Potentilla discolor Bge. was determined by HPLC. Results: The optimum conditions of ultrasonics extraction are as follow: ethanol concentration 75%, time 60 min, ratio of material to solution 1:60, and power of extraction 610 W. The effects of factors on yield decrease progressively in the following order: extracting timeratio of material to solutionethanol concentrationpower of extraction. Conclusion: The best optimized process has a good repeatability confimatory experiment.
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Objective: To screen optimum the extraction process of ursolic acid from Potentilla discolor Bge. Methods: ultrasonics extraction was used to extract. The optimum extraction process was confimed by the orthogonal test. The content of ursolic acid in Potentilla discolor Bge. was determined by HPLC. Results: The optimum conditions of ultrasonics extraction are as follow: ethanol concentration 75%, time 60 min, ratio of material to solution 1:60, and power of extraction 610 W. The effects of factors on yield decrease progressively in the following order: extracting timeratio of material to solutionethanol concentrationpower of extraction. Conclusion: The best optimized process has a good repeatability confimatory experiment.
Key concepts: Ursolic acid, Potentilla, Extraction (chemistry), Chromatography, Repeatability, Yield (engineering), Chemistry, Botany