Variation of serum immune status of children with recurrent respiratory tract infections

OBJECTIVE To investigate the variation of the serum immune status of the children with recurrent respiratory tract infections.METHODS A total of 51 children with recurrent respiratory tract infections who were treated in hospital from Jan 2009 to Jun 2011 in the hospital were chosen as the research objects and set as the observation group,and 51 healthy children at the same period were selected as the control group.The peripheral blood T lymphocyte subsets,the level of immunoglobulin and the level of immune factors in erythrocyte of the children in the two groups were tested and compared.RESULTS The CD3+(53.37 ±3.61)%,CD4+(42.25±3.49)%,CD8+(33.23±2.19)% and IgA(6.05±0.79) mg/L,IgM(9.17±1.09)mg/L,IgG(6.15±0.22)g/L,the C3b receptor rosette rate(11.05±1.63)%,and the immune adhesion-promoting factor(42.56±2.51)% of the observation group were lower than those of the control group.The CD4/CD8(1.27±0.19),immune complex rosette rate(4.53±0.22)% and immune adherence inhibitory factor(35.13±1.95)% of the observation group were higher than those of the control group,and the differences in the exacerbation and remission were statistically significant(P0.05).CONCLUSION The variation of the serum immune status of the children with recurrent respiratory tract infections is significant,which is closely associated with the stage.