Effects of Long-term Ionizing Radiation on T,B and NK Lymphocyte Subsets in Peripheral Blood of Male Roentgenogramphy Workers
Xiaoguang Liu
Abstract
Xiaoguang Liu
Abstract
[Objective]To investigate the effects of long-term ionizing radiation on T,B and NK lymphocyte subsets in peripheral blood of male roentgenography workers.[Methods]The T,B and NK lymphocyte subsets in the peripheral blood lymphocyte of 32 male roentgenography workers were examined and compared among stratified groups with gradient radiation dose.[Results]There were significant difference(t= 2.430,P0.05) between the percents of CD3~+CD8~+T cells in lymphocyte of≤20mSv group[(24.91±7.21)%]versus20mSv group[(18.68±6.99)%].The percents of CD8~+CD45RO~+T cells in lymphocyte between≤20mSv group[(6.54±2.65)%]versus20mSv group[(4.15±1.93)%]were significantly different also(t=2.780,P0.01).[Conclusion]Reduction of CD3~+CD8~+T and CD8~+CD45RO~+T subsets of lymphocyte may be resulted in long-term ionizing radiation in male roentgenography workers.Attention in monitoring on these changes should be enforced.
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[Objective]To investigate the effects of long-term ionizing radiation on T,B and NK lymphocyte subsets in peripheral blood of male roentgenography workers.[Methods]The T,B and NK lymphocyte subsets in the peripheral blood lymphocyte of 32 male roentgenography workers were examined and compared among stratified groups with gradient radiation dose.[Results]There were significant difference(t= 2.430,P0.05) between the percents of CD3~+CD8~+T cells in lymphocyte of≤20mSv group[(24.91±7.21)%]versus20mSv group[(18.68±6.99)%].The percents of CD8~+CD45RO~+T cells in lymphocyte between≤20mSv group[(6.54±2.65)%]versus20mSv group[(4.15±1.93)%]were significantly different also(t=2.780,P0.01).[Conclusion]Reduction of CD3~+CD8~+T and CD8~+CD45RO~+T subsets of lymphocyte may be resulted in long-term ionizing radiation in male roentgenography workers.Attention in monitoring on these changes should be enforced.
Key concepts: CD8, Ionizing radiation, Peripheral blood, Lymphocyte subsets, Lymphocyte, T lymphocyte, CD3, Peripheral blood lymphocyte