Clinical study on post-stroke depression

Objective:To investigate the incidence and its risk factors of post-stroke depression (PSD) in cerebral stroke patients at acute stage.Methods:127 stroke patients consecutive admitted to hospital within 72 h onset were divided into PSD group and non-PSD group according to the scores of 17-item Hamilton Depression Rating scale (HAMD) in the 14 d after admission.The relationship between PSD and clinical factors including sex,marital status,age,education,stroke type,lesionlocation,hypertension,diabetes,coronaryarterydisease,smoking,drinking,BMI,family history of stroke,score of National Institutes of Health Stroke Scale (NIHSS),Barthel Index (BI),and score of mini mental statue examination (MMSE) were analyzed.Results:The PSD incidence in this group was 36.2%(46 cases).In PSD group,man were easier to hypertension,the infarct volume and scores of BI on admission were significantly higher,BI and score of MMSE on admission were significantly lower than non-PSD group (P0.05 or 0.01).Conclusion:The incidence of PSD in patients with cerebal stroke at acute stage is high.The cerebral infarction,hypertension and BI on admission are the independent risk factors of PSD.