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2003•Chinese Journal of Laboratory DiagnosisRequires access

Delection of serum of hepatic fibrosis in patients with hepatits and hepatocirrhosis

Jiang Xiu

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Abstract

Objective To the serum levels of TGF β 1, IL 1,HA,IV C,PⅢP and their correlations with hepatic fibrosis in patients with hepatitis.Methods TGF β 1,IL 1, HA,LN,IV C,PⅢP were detected by ELISA and RIA. Results The results showed that TGF β 1 and IL 1 levels were significantly highter in patients with chronic hepatitis and hepatocirrhosis compared with normal subjects.The serum levels of TGF β 1 and IL 1 in viral hepatitis were closely related to the levels of serum HA, LN,IV C and PⅢP. Conclusion These results suggested that the change of TGF β 1 and IL 1 may be related to the pathogenesis of hepatic fibrosis.It may play an important role in the process from chronic hepatitis to cirrhosis.

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What this paper is about

Objective To the serum levels of TGF β 1, IL 1,HA,IV C,PⅢP and their correlations with hepatic fibrosis in patients with hepatitis.Methods TGF β 1,IL 1, HA,LN,IV C,PⅢP were detected by ELISA and RIA. Results The results showed that TGF β 1 and IL 1 levels were significantly highter in patients with chronic hepatitis and hepatocirrhosis compared with normal subjects.The serum levels of TGF β 1 and IL 1 in viral hepatitis were closely related to the levels of serum HA, LN,IV C and PⅢP. Conclusion These results suggested that the change of TGF β 1 and IL 1 may be related to the pathogenesis of hepatic fibrosis.It may play an important role in the process from chronic hepatitis to cirrhosis.

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Available abstract

Objective To the serum levels of TGF β 1, IL 1,HA,IV C,PⅢP and their correlations with hepatic fibrosis in patients with hepatitis.Methods TGF β 1,IL 1, HA,LN,IV C,PⅢP were detected by ELISA and RIA. Results The results showed that TGF β 1 and IL 1 levels were significantly highter in patients with chronic hepatitis and hepatocirrhosis compared with normal subjects.The serum levels of TGF β 1 and IL 1 in viral hepatitis were closely related to the levels of serum HA, LN,IV C and PⅢP. Conclusion These results suggested that the change of TGF β 1 and IL 1 may be related to the pathogenesis of hepatic fibrosis.It may play an important role in the process from chronic hepatitis to cirrhosis.

Key concepts: Cirrhosis, Fibrosis, Pathogenesis, Hepatic fibrosis, Medicine, Chronic hepatitis, Internal medicine, Viral hepatitis

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Delection of serum of hepatic fibrosis in patients with hepatits and hepatocirrhosis — Research Paper | ScholarLens