Effects of Danhong Injection (丹红注射液) Combining with Folic Acid on S100β,Homocysteine and High Sensitivity C-Reactive Protein in Patients with Cerebral Infarction

Objective: To observe the efficacy of Danhong Injection combined with folic acid in patients with cerebral infarction,and its impact on the levels of S100β,homocysteine( Hcy) and high sensitivity C- reactive protein( hs- CRP). Methods: 400 patients with cerebral infarction were randomly divided into observation group and control group,each group had 200 cases. The control group were treated with folic acid,the observation group were gave Danhong Injection on the basis of the control group. The efficacy were observed after treatment,and the levels of S100β,Hcy and hs- CRP were detected before or after treatment. Results: The total effective rate was 95. 50% in observation group that was significantly better than 75. 50% in the control group,the difference was statistically significant( χ2= 17. 258,P 0. 05). The NIHSS score,S100β,Hcy and hs- CRP levels in two groups were significantly lower after treatment compared with those before treatment( P 0. 01),effcts in observation group was significantly more obvious( P 0. 01). The ADL score was significantly higher than those before treatment( P 0. 01),elevated levels of observation group was significantly more obvious( P 0. 01). Conclusion: The efficacy and prognosis of Danhong Injection combining with folic acid in patients with cerebral infarction are improved obviously,their mechanism may be closely related to down- negulat the levels of Hcy,S100β and hs- CRP.