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Clinical Observation of 108 Cases on Seretide in Treating Bronchial Asthma

Yuyong Tan

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Abstract

Objective To approach the therapeutic action of Seretide in treating bronchial asthma.Methods 108 patients with bronchial asthma,were randomly divided into treatment and control groups(each group of 54 patients).Treatment group were treated with inhaled corticosteroids(beclomethasone)and oral terbutaline,and Seretide(salmeterol / fluticasone),2 times / day.Control group were treated with inhaled beclomethasone and oral terbutaline.Observed for 12 weeks,the rate observed for clinical control of asthma,forced expiratory volume in one second(FEV1),self-test peak expiratory flow(PEF)and adverse drug reactions.Results Treatment group 34 patients(62.9%)achieved clinical control.Compared with the control group of 20 patients(37.0%),the difference was significant(P0.05),after treatment,FEV1,PEF were higher than pre-treatment levels(P0.05).Conclusion Seretide have a sure effect in treating bronchial asthma,it can effectively improve clinical symptoms and reduce the relapse rate.And it is better than only application of inhaled corticosteroids in treating bronchial asthma.

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Objective To approach the therapeutic action of Seretide in treating bronchial asthma.Methods 108 patients with bronchial asthma,were randomly divided into treatment and control groups(each group of 54 patients).Treatment group were treated with inhaled corticosteroids(beclomethasone)and oral terbutaline,and Seretide(salmeterol / fluticasone),2 times / day.Control group were treated with inhaled beclomethasone and oral terbutaline.Observed for 12 weeks,the rate observed for clinical control of asthma,forced expiratory volume in one second(FEV1),self-test peak expiratory flow(PEF)and adverse drug reactions.Results Treatment group 34 patients(62.9%)achieved clinical control.Compared with the control group of 20 patients(37.0%),the difference was significant(P0.05),after treatment,FEV1,PEF were higher than pre-treatment levels(P0.05).Conclusion Seretide have a sure effect in treating bronchial asthma,it can effectively improve clinical symptoms and reduce the relapse rate.And it is better than only application of inhaled corticosteroids in treating bronchial asthma.

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Available abstract

Objective To approach the therapeutic action of Seretide in treating bronchial asthma.Methods 108 patients with bronchial asthma,were randomly divided into treatment and control groups(each group of 54 patients).Treatment group were treated with inhaled corticosteroids(beclomethasone)and oral terbutaline,and Seretide(salmeterol / fluticasone),2 times / day.Control group were treated with inhaled beclomethasone and oral terbutaline.Observed for 12 weeks,the rate observed for clinical control of asthma,forced expiratory volume in one second(FEV1),self-test peak expiratory flow(PEF)and adverse drug reactions.Results Treatment group 34 patients(62.9%)achieved clinical control.Compared with the control group of 20 patients(37.0%),the difference was significant(P0.05),after treatment,FEV1,PEF were higher than pre-treatment levels(P0.05).Conclusion Seretide have a sure effect in treating bronchial asthma,it can effectively improve clinical symptoms and reduce the relapse rate.And it is better than only application of inhaled corticosteroids in treating bronchial asthma.

Key concepts: Medicine, Asthma, Fluticasone, Salmeterol, Terbutaline, Anesthesia, Budesonide, Internal medicine

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