Analysis on pathogenic bacteria distribution and drug-resistance in moderate and severe hypertensive patients with upper respiratory tract infections

OBJECTIVE To analyze pathogenic bacteria distribution and drug resistance in patients with moderate and severe hypertension of upper respiratory tract infections,so as to provide the reference for clinical reasonable use of antibiotics for treatment.METHODS In our hospital,100cases of hypertension complicated with upper respiratory infection from Mar.2010to Mar.2012admitted to our hospital were selected and treated by fullautomatic blood culture system DL-Bt1122to isolate and culture pathogenic bacteria.RESULTS A total of 127 strains of pathogenic bacteria were detected from 100 patients,including gram positive bacteria 23strains(18.11%),among which Staphylococcus aureus,Streptococcus pneumoniae and Enterococcus faecalis were the top three,accounting for 7.08%,3.94%,2.36%,respectively.Gram negative bacteria 104strains(81.89%), among which Klebsiella pneumoniae,Escherichia coli and Pseudomonas aeruginosa were the top three, accounting for 25.20%,14.96%,11.81%,respectively.Drug resistance rates of gram positive bacteria to cefazolin,sulfamethoxazole-trimethoprim,levofloxacin and flucloxacillin were higher than 80.00%,while to ceftizoxime and vancomycin were lower,accounting for 33.33%and 0respectively.Drug resistance rates of gram negative bacteria to meropenem(92.86%),ceftriaxone(78.95%)and cefazolin(89.48%)were higher,while to gentamicin(38.46%)was low.CONCLUSIONThe clinical need to treat upper respiratory tract infections occurred in hypertensive patients as a key monitoring of hospital infections.Once the infection occurs,the pathogenic bacteria of this infection should be clear and sensitive antibiotics should be used for treatment.In addition, management of antibiotics using in hospital should be strengthened.