2002•Journal of Zibo UniversityRequires access

Advance for the Study on Immunological Mechanism and Antigen of Mycobacterium Tuberculosis

Honghai Wang

Abstract

M. tuberculosis is a facultative intracellular pathogen. Extracellular proteins of M. tuberculosis induce a strong T cell-mediated immune response. Cell mediated immunity (CMI) as opposed to humoral immunity play a dominant in host defense against M. tuberculosis. The identification of specific and protective antigens of M. tuberculosis can be applied in tuberculosis diagnosis and vaccine construction.

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Available abstract

Key concepts: Tuberculosis, Mycobacterium tuberculosis, Antigen, Intracellular parasite, Immunology, Immune system, Immunity, Pathogen