2007•Zhongguo yaofangRequires access

Cost-Effectiveness Analysis of Three Therapeutic Schemes for Lower Respiratory Tract Infection

Limin Dong

Abstract

OBJECTIVE:To compare the pharmacoeconomic effects of three antibacterial drug therapies for the treatment of lower respiratory tract infection(LRTI).METHODS:A total of 110 LRTI patients were randomized to Group A(azithromyc-in),Group B(amoxicillin/sulbactam) or Group C(levofloxacin) with a course of treatment at 10 days for each Group.A cost-effectiveness analysis was conducted for the evaluation of the three schemes.RESULTS:The total costs of three schemes were 640.00 yuan,696.00 yuan and 376.00 yuan,respectively;the effective rate were 83.3%,85.7% and 82.1%,respectively(P0.05);the cost-effectiveness ratios were 768.31,812.14 and 457.98,respectively.CONCLUSION:Scheme C was proved to be the best therapeutic regime.

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Key concepts: Levofloxacin, Medicine, Lower respiratory tract infection, Amoxicillin, Respiratory tract infections, Internal medicine, Cost-effectiveness analysis, Antibiotics