2009Journal of Clinical RadiologyRequires access

Evaluation and Analysis of MRI,Sonography and Tumor Markers of Serum in the Diagnosis of Uterine Adenomyosis

Hualiang Li

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Abstract

Objective To investigate the role of MRI,sonography and tumor markers of serum in the diagnosis of uterine adenomyosis.Materials and Methods MRI,sonography(transabdominal and transvaginal sonography)and estimation of serum CA125,CA199 and CA153 levels were carried out in 45 patients confirmed pathologically as uterine adenomyosis and 36 patents with leiomyoma before operation.The sensitivity,specificity and accuracy were analyzed respectively.Results The sensitivity,specificity and accuracy of MR in the diagnosis of uterine adenomyosis were 95.56%,100% and 97.53%,those of TVS were 80.0%,88.89% and 83.95%,those of TAS were 68.89%,83.33% and 75.31%,those of serum CA125 levels were 46.67%,88.89% and 65.43%,those of serum CA153 levels were 33.33%,94.44% and 60.49%,those of serum of CA199 levels were 15.56%,97.22% and 51.85%.The difference was much significant on sensitivity and accuracy in diagnosing the uterine adenomyosis and not significant on specificity.Conclusion MRI,sonography and tumor markers of serum are helpful to diagnose the uterine adenomyosis.However,MRI,transvaginal and transabdominal sonography are superior to CA125,CA199 and CA153 of serum,MRI is the best modality of them.

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Objective To investigate the role of MRI,sonography and tumor markers of serum in the diagnosis of uterine adenomyosis.Materials and Methods MRI,sonography(transabdominal and transvaginal sonography)and estimation of serum CA125,CA199 and CA153 levels were carried out in 45 patients confirmed pathologically as uterine adenomyosis and 36 patents with leiomyoma before operation.The sensitivity,specificity and accuracy were analyzed respectively.Results The sensitivity,specificity and accuracy of MR in the diagnosis of uterine adenomyosis were 95.56%,100% and 97.53%,those of TVS were 80.0%,88.89% and 83.95%,those of TAS were 68.89%,83.33% and 75.31%,those of serum CA125 levels were 46.67%,88.89% and 65.43%,those of serum CA153 levels were 33.33%,94.44% and 60.49%,those of serum of CA199 levels were 15.56%,97.22% and 51.85%.The difference was much significant on sensitivity and accuracy in diagnosing the uterine adenomyosis and not significant on specificity.Conclusion MRI,sonography and tumor markers of serum are helpful to diagnose the uterine adenomyosis.However,MRI,transvaginal and transabdominal sonography are superior to CA125,CA199 and CA153 of serum,MRI is the best modality of them.

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Available abstract

Objective To investigate the role of MRI,sonography and tumor markers of serum in the diagnosis of uterine adenomyosis.Materials and Methods MRI,sonography(transabdominal and transvaginal sonography)and estimation of serum CA125,CA199 and CA153 levels were carried out in 45 patients confirmed pathologically as uterine adenomyosis and 36 patents with leiomyoma before operation.The sensitivity,specificity and accuracy were analyzed respectively.Results The sensitivity,specificity and accuracy of MR in the diagnosis of uterine adenomyosis were 95.56%,100% and 97.53%,those of TVS were 80.0%,88.89% and 83.95%,those of TAS were 68.89%,83.33% and 75.31%,those of serum CA125 levels were 46.67%,88.89% and 65.43%,those of serum CA153 levels were 33.33%,94.44% and 60.49%,those of serum of CA199 levels were 15.56%,97.22% and 51.85%.The difference was much significant on sensitivity and accuracy in diagnosing the uterine adenomyosis and not significant on specificity.Conclusion MRI,sonography and tumor markers of serum are helpful to diagnose the uterine adenomyosis.However,MRI,transvaginal and transabdominal sonography are superior to CA125,CA199 and CA153 of serum,MRI is the best modality of them.

Key concepts: Adenomyosis, Medicine, Radiology, Leiomyoma, Diagnostic accuracy, Gynecology, Endometriosis

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Evaluation and Analysis of MRI,Sonography and Tumor Markers of Serum in the Diagnosis of Uterine Adenomyosis — Research Paper | ScholarLens