Relation of Cerebral Infarction with Blood Pressure, Blood Lipids, Blood Glucose, Homocysteine and hs-C-reactive Protein Levels

Objective: To explore the relation of blood pressure, blood lipids, blood glucose, glycated hemoglobin, homocysteine(HCY) and high sensitivity-C-reactive protein(hs-CRP) and the risk of cerebral infarction, to provide theoretical basis for preventing the onset and early diagnosis of cerebral infarction. Methods: This is a retrospective case-control study with 256 cerebral infarction patients and 216 healthy controls. The automatic biochemical analyzer was used to detect the biochemical parameters of the participants and then analyzed the parameters with SPSS 20.0. In addition, the cerebral infarction group was divided into three groups: simple cerebral infarction group, the group with hypertension, the group with diabetes and the normal control group, which were compared with lipid levels, respectively. Results: There were significant differences of blood pressure, total cholesterol(TC), triglyceride(TG), low density lipoprotein cholesterol(LDL-C), high density lipoprotein cholesterol(HDL-C), homocysteine, glucose, hs-CRP levels and total cholesterol / high-density lipoprotein cholesterol(TC/HDL-C) ratio between cases and controls(P0.05). Meanwhile, lipids(TC, TG,LDL-C, TC/HDL-C) levels in three different groups of cases were significantly higher than those in the controls, however HDL-C levels were significantly lower than those in the controls(P0.05). Conclusion: High blood pressure, high HCY, high blood glucose, high hs-CRP levels and dyslipidemia were associated with the risk of cerebral infarction, detecting the above indicators have great significances for the prevention and treatment of cerebral infarction.