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Study on Pharmacokinetics of Isoimpteratorin in Dogs

Bao Yu-long

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Abstract

Objective: To Study the Pharmacokinetics of isoimpteratorin in Dogs.Methods:The concentrations of isoimpteratorin were determined by HPLC with Fluorescence Detection,pharmacokinetics parameter was calculated by DAS(ver2.0)pharmacoktnetics procedure.Results:The Pharmacokinetics parameters of isoimpteratorin after single ig in dogs are as follows: AUC 0-9 is 1.827mg/(L·h),Cmax is 0.835mg/L,Tmax is 20min,t1/2is 1.5h.Conclusion:The absorption of isoimpteratorin in dogs is of first order kinetics.

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Objective: To Study the Pharmacokinetics of isoimpteratorin in Dogs.Methods:The concentrations of isoimpteratorin were determined by HPLC with Fluorescence Detection,pharmacokinetics parameter was calculated by DAS(ver2.0)pharmacoktnetics procedure.Results:The Pharmacokinetics parameters of isoimpteratorin after single ig in dogs are as follows: AUC 0-9 is 1.827mg/(L·h),Cmax is 0.835mg/L,Tmax is 20min,t1/2is 1.5h.Conclusion:The absorption of isoimpteratorin in dogs is of first order kinetics.

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Available abstract

Objective: To Study the Pharmacokinetics of isoimpteratorin in Dogs.Methods:The concentrations of isoimpteratorin were determined by HPLC with Fluorescence Detection,pharmacokinetics parameter was calculated by DAS(ver2.0)pharmacoktnetics procedure.Results:The Pharmacokinetics parameters of isoimpteratorin after single ig in dogs are as follows: AUC 0-9 is 1.827mg/(L·h),Cmax is 0.835mg/L,Tmax is 20min,t1/2is 1.5h.Conclusion:The absorption of isoimpteratorin in dogs is of first order kinetics.

Key concepts: Pharmacokinetics, Cmax, Medicine, Pharmacology, Absorption rate, Absorption (acoustics), High-performance liquid chromatography, Chromatography

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