2012Laboratory Medicine and ClinicRequires access

Analysis of the infection and drug resistance from 2613 patients with genitourinary tract mycoplasma infection of Non-Neisseria gonorrhoeae

Zheng Ding

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Abstract

Objective To explore the Non Neisseria gonorrhoeae of genitourinary tract mycoplasma infection and drug resistance in this region,and to provide the basis for clinical rational drug use.Methods 2 613 cases of genitourinary tract specimens were trained and 12 kinds of antibiotic susceptibility were tested.Results There were 1 428 cases of positive in mycoplasma,and the positive rate was 54.6%,while the rate of ureaplasma urealyticum(Uu),mycoplasma hominis(Mh) and Uu + Mh of mixed infection were 45.4%,1.4% and 7.8% respectively.The infection rate was 29.0% in male and 62.0% in female,and the difference was statistically significant(P0.01);The results of drug sensitive test showed,josamycin,doxycycline and tetracycline have high antibacterial activity or mycoplasma.And clarithromycin,azithromycin,roxithromycin had good antimicrobial activity only for a single Uu infection.Conclusion Mycoplasma is a common pathogens for genitourinary system of inflammation.It was primarily infected by Uu,and the rate of infection in women was higher than that in man.Clinicians should chose proper antibiotic according to antimicrobial susceptibility test results,to reduce the generation of drug resistant strains.

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Objective To explore the Non Neisseria gonorrhoeae of genitourinary tract mycoplasma infection and drug resistance in this region,and to provide the basis for clinical rational drug use.Methods 2 613 cases of genitourinary tract specimens were trained and 12 kinds of antibiotic susceptibility were tested.Results There were 1 428 cases of positive in mycoplasma,and the positive rate was 54.6%,while the rate of ureaplasma urealyticum(Uu),mycoplasma hominis(Mh) and Uu + Mh of mixed infection were 45.4%,1.4% and 7.8% respectively.The infection rate was 29.0% in male and 62.0% in female,and the difference was statistically significant(P0.01);The results of drug sensitive test showed,josamycin,doxycycline and tetracycline have high antibacterial activity or mycoplasma.And clarithromycin,azithromycin,roxithromycin had good antimicrobial activity only for a single Uu infection.Conclusion Mycoplasma is a common pathogens for genitourinary system of inflammation.It was primarily infected by Uu,and the rate of infection in women was higher than that in man.Clinicians should chose proper antibiotic according to antimicrobial susceptibility test results,to reduce the generation of drug resistant strains.

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Available abstract

Objective To explore the Non Neisseria gonorrhoeae of genitourinary tract mycoplasma infection and drug resistance in this region,and to provide the basis for clinical rational drug use.Methods 2 613 cases of genitourinary tract specimens were trained and 12 kinds of antibiotic susceptibility were tested.Results There were 1 428 cases of positive in mycoplasma,and the positive rate was 54.6%,while the rate of ureaplasma urealyticum(Uu),mycoplasma hominis(Mh) and Uu + Mh of mixed infection were 45.4%,1.4% and 7.8% respectively.The infection rate was 29.0% in male and 62.0% in female,and the difference was statistically significant(P0.01);The results of drug sensitive test showed,josamycin,doxycycline and tetracycline have high antibacterial activity or mycoplasma.And clarithromycin,azithromycin,roxithromycin had good antimicrobial activity only for a single Uu infection.Conclusion Mycoplasma is a common pathogens for genitourinary system of inflammation.It was primarily infected by Uu,and the rate of infection in women was higher than that in man.Clinicians should chose proper antibiotic according to antimicrobial susceptibility test results,to reduce the generation of drug resistant strains.

Key concepts: Ureaplasma urealyticum, Mycoplasma, Josamycin, Roxithromycin, Neisseria gonorrhoeae, Microbiology, Genitourinary system, Mycoplasma hominis

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Analysis of the infection and drug resistance from 2613 patients with genitourinary tract mycoplasma infection of Non-Neisseria gonorrhoeae — Research Paper | ScholarLens