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2010•Journal of Tianjin University of Traditional Chinese MedicineRequires access

Research on Quality Standard of Xinshuning Tablets

Yan Zhang

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Abstract

[Objective] To establish quality standard of Xinshuning tablets.[Method] Lignum Santali Albi and Radix et Rhizoma Notoginseng were identified by microscopic identification;Radix et Rhizoma Notoginseng and Salviae Miltiorrhizae were identified by TLC;The content of danshensu was determined by HPLC.[Results] The microscopic characteristics were notable;The TLC sports developed were fairly clear,and the blank test showed no interference;Linearity range of danshensu was 0.198-3.168 μg(r=0.9998).The average recovery was 97.4% and RSD was 1.26%(n=6).[Conclusion] The methods are simple,accurate and reproducible.It can be quality standard of Xinshuning tablets.

About this research paper

What this paper is about

[Objective] To establish quality standard of Xinshuning tablets.[Method] Lignum Santali Albi and Radix et Rhizoma Notoginseng were identified by microscopic identification;Radix et Rhizoma Notoginseng and Salviae Miltiorrhizae were identified by TLC;The content of danshensu was determined by HPLC.[Results] The microscopic characteristics were notable;The TLC sports developed were fairly clear,and the blank test showed no interference;Linearity range of danshensu was 0.198-3.168 μg(r=0.9998).The average recovery was 97.4% and RSD was 1.26%(n=6).[Conclusion] The methods are simple,accurate and reproducible.It can be quality standard of Xinshuning tablets.

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Available abstract

[Objective] To establish quality standard of Xinshuning tablets.[Method] Lignum Santali Albi and Radix et Rhizoma Notoginseng were identified by microscopic identification;Radix et Rhizoma Notoginseng and Salviae Miltiorrhizae were identified by TLC;The content of danshensu was determined by HPLC.[Results] The microscopic characteristics were notable;The TLC sports developed were fairly clear,and the blank test showed no interference;Linearity range of danshensu was 0.198-3.168 μg(r=0.9998).The average recovery was 97.4% and RSD was 1.26%(n=6).[Conclusion] The methods are simple,accurate and reproducible.It can be quality standard of Xinshuning tablets.

Key concepts: Radix (gastropod), Quality standard, Chromatography, High-performance liquid chromatography, Medicine, Traditional medicine, Chemistry, Biology

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