Clinical observation of sequential moxifloxacin method on lower respiratory tract infection in old patients

Objective To evaluate the efficacy on sequential therapy with moxifloxacin for lower respiratory tract infection in old patients.Methods A total of 58 patients were divided into 2 groups.The treatment group(n=30) was given 400 mg of moxifloxacin intravenously,once a day,and the control group(n=28) was given 1.5 g of cefuroxime intravenously,twice a day.Two groups took congeneric medicine orally when their symptoms of disease were improved.Results The clinical effective rates of moxifloxacin and cefuroxime were 93.3% and 71.4%,respectively(P0.05).The bacterial clearance rates of moxifloxacin and cefuroxime were 94.4% and 76.5%,respectively(P0.05).The incidences of adverse reaction of moxifloxacin and cefuroxime were 6.7% and 7.1%,respectively(P0.05).Conclusion Moxifloxacin is an effective and safe antibiotic in sequential therapy for the old patients with lower respiratory tract infection.