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Chemical constituents of ethyl acetate fraction from Platycodon grandiflorum

Danni Zhu

Abstract

Objective: To study the chemical constituents of ethyl acetate fraction from Platycodon grandiflorum(Jacq.)A.DC.Method: Chemical constituents were isolated by chromatographic methods and identified by NMR analysis.Results: Nine compounds are oleanolic acid(1),friedelinol(2),negletein(3),daucosterol(4),α-spinasterol(5),α-spinasterol-3-O-β-D-glucopy ranoside(6),betulin(7),stigmasta-7-dien-3β-ol(8),β-sitosterol(9).Conclusion: Compound 1,2,3 and 4 are isolated from this plant for the first time.

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Key concepts: Daucosterol, Oleanolic acid, Chemistry, Ethyl acetate, Chemical constituents, Fraction (chemistry), Chromatography, Betulin