Study on the Method for Determining Migration of Melamine from Melamine-Formaldehyde Containers by HPLC

[Objective] To develop a rapid and simple high-performance liquid chromatography(HPLC) method for determining the migration of melamine extracted by four solvents from melamine-formaldehyde products used as food containers.[Methods] Melamine were soaked out by four solvents which were water,4% acetic acid,15% ethanol and n-hexane.The four soaks were separated by reversed phase chromatographic column and detected by UV-detector.[Results] The analysis method of determining the migration of melamine from melamine-formaldehyde food containers was studied from the aspects of chromatogram and soaking solutions.The detection limit was 10 μg/dm2.The linear range was between 0.050 μg/mL and 2.000 μg/mL.The recovery was controlled between 85.7% and 105.7%.The relative standard deviation was between 0.43% and 4.80%.[Conclusion] This method was rapid,effective,stabilize and sensitive for detecting the migration of melamine from melamine-formaldehyde products used as food containers.