Application of modified Baihu decoction(白虎汤) in treatment of infective fever after renal transplantation

Objective: To analyze the reason, diagnose and treatment of high fever caused by infection after renal transplantation, and investigate the mechanism of integrated traditional Chinese and western medicine therapy in treating high fever after renal transplantation. Methods: Thirtytwo patients after renal transplantation were divided into two groups. The treatment group was treated with traditional Chinese medicine Baihu decoction(白虎汤), hormone, antivirus and antigerm treatment. At the same time the dosage of cyclosporin(CsA) was reduced, cellular toxic medicine was stopped using and whole body support treatment was used. The control group wasn't treated with traditional Chinese medicine. The other therapy was the same in the two groups. Results: Of 15 cases in the treatment group, 14 cases recovered, 1 case improved, the cured rate was 93%. Of 17 cases in the control group, 9 cases recovered, 1 case improved, 7 cases died, the cured rate was 53%. The cured rate of the two groups had significant difference(P0 05). Conclusion: The patient after renal transplantation appears evil fire fulled the three cavities, though evil heat is strong, body fluids are not damaged. Baihu decoction has the effect of getting rid of fever and agitation, producing fluids and preventing thirsty, reducing temperature and antiinflammation etc. It has the effect in the patients with high fever, extreme thirsty, pulse quickly. After renal transplantation, the infective fever caused by low immune can be effectively controlled with Baihu decoction, antigerm western medicine and whole body support therapy.