Clinical Observation of Rabeprazole Quadruple Therapy Treatment of Helicobacter Pylori Infection Peptic Ulcer

Objective to observe the rabeprazole quadruple therapy treatment of peptic ulcer and effect on helicobacter pylori infection eradication rate.Methods choose from the gastroscopy confirmed and 14C urea breath test positive of 64 cases of peptic ulcer patients,random divided into treatment group and control group,the 32 cases of the treatment group was given rabeprazole,amoxicillin,furazolidone,pectic bismuth,7 days treatment,pectic bismuth plus take 1 week,then separate give rabeprazole to continue treatment;Control group;bismuth pectin,amoxicillin,furazolidone 7 days after treatment,alone give pectic bismuth;Two groups of total treatment duodenal ulcer,DU 4 weeks,gastric ulcer GU 6 weeks,after the treatment the gastroscope and helicobacter pylori to evaluate curative effect.Results two groups of main symptoms change and abdominal pain disappeared time is,the difference was statistically significant(P0.05);The treatment group and the control group total effective rate was 96.88% and 78.13%,respectively,between the two groups(P0.05);The treatment group and the control group HP eradicate rate was 93.75% and 71.88%,respectively,between the two groups(P0.05);The treatment group and the control group adverse reaction rate were 3.13% and 3.13% respectively,the difference was not statistically significant.Conclusion rabeprazole,amoxicillin,furazolidone,pectic bismuth quadruple therapy can obviously alleviate the symptoms of peptic ulcer,analgesic effect fast,fewer side effects,peptic ulcer have higher cure rate and the rate of helicobacter pylori infection.