Study on endometrium morphologic change before and after treatment in 12 cases of PCOS.

Objective To investigate the ultrasonic and pathological characteristics of the endometrium and the relationship with sexual hormones,obesity index in polycystic ovary syndrome(PCOS) patients.Methods Endometrium biopsy was done in the 12 PCOS patients received ovulation induction therapies and the seven nomal women with regular menstruation during implanting window time.then to study the ultra-sonic and pathology features of endometrium.Results(1)Routine HE staining of endometrium:there was significant difference of percentage of endometrial sample with poor response of stroma and secretion deficiency between PCOS patients and control group(P0.05).(2)The endometrial thickness of PCOS patients was slightly lower than that of control group,but there was no significant difference(P0.05).The frequency of type A endometrium,PCOS patients was significantly lower than that of control group(P0.05).Conclusion There are significant changes in features and function of PCOS endometrium,which induce the defect of endometrial receptivity.