2005•Chinese Clinical OncologyRequires access

Relationship Between Expression of E-cadherin in Gastric Carcinoma and its Clinicopathological Features

Yu Huang

Abstract

Objective:To study the relationship between the expression of E-cadherin and invasion,metastasis and progression of human gastric cancer.Methods:76 cases of human gastric cancer were examined for E-cadherin by SP immunohistochemistry.Results:E-cadherin was present in all normal gastric mucomembranous epithelium.E-cadherin was associated with gastric cancer differentiation,invasion and metastasis (P0.01).Conclusion:E-cadherin is associated with gastric cancer differentiation,invasion and metastasis,which suggests E-cadherin as a new tumor marker.

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Key concepts: Cadherin, Immunohistochemistry, Metastasis, Medicine, Cancer, Pathology, Gastric carcinoma, Cancer cell