The Clinical Study of the Different Compatibility of Drugs During Painless Artificial Abortion of Early Pregnancy

Objective To study the best clinical effect on termination of early pregnancy by giving the different compatibility of drugs during painless artificial abortion. Methods 800 women with ASA class I who asked for painless artificial abortion were divided randomly into four groups: A group(200 cases) were intravenous injected with fentanyl 50μg, and diazepam 10㎎ before operation, B group(200 cases) with fentanyl 50μg, atropine 0.2㎎ and propofol 2.0-2.5㎎/kg before operation, C group(200 cases) with fentanyl 20μg, atropine 0.2㎎ and propofol , D group(200 cases) with fentanyl 20μg, diazepam 5㎎, atropine 0.2㎎ and propofol 2.0-2.5㎎/kg before operation. The analgesic effect, respiratory and circulatory system complications were observed in four groups. Results There was the best analgesic effect in B group, the difference between B and the others was significant(p0.05), but respiratory and circulatory system complications had no significant difference among four groups(p0.05). Conclusions The analgesic effect by fentanyl 50μg, atropine 0.2㎎ and propofol 2.0-2.5㎎/kg is satisfied for artificial abortion. It's one of better ways for the artificial abortion analgesic.