ScholarLens Back to search
2001•HereditasRequires access

Rat Gene Polymorphism Using PC R一Analyzed Microsatellites

Ruisheng Li, CHENZheirwen, Deguang Song, Weirzhi Ren, Luan Ronghui

Open publisher page 1 citations

Abstract

In the experiment ,It were selected that 20 primers were assigned on 7 chromosomes of inbred rat.DNA polymorphism of 8 colonies from 6 inbred rat strains(SHR.SHRSP、WKY.LEW.RCS.F344) were studied in national Beijing and Harbin using PCR一analyzed microsatellites .The results indicated that there were remarkable polymorphism in 9 microsatellite loci ;There is apolymorphism among the various rat strains ;and no polymorphism in the same rat strains except SMST locus of SHR(Harbin) and AGT locus of WKY( Harbin) and there is a little difference among the same inbred rat strains in different areas . The method of PCR 一analyzed microsatellites can be used for distinguishing between inbred and outbred .different strains .strain and substrain .and it provides a lot of information for genetic mapping ,gene location and heredity probe of the inbred rat strains ,and a speedy.conve-nient method for genetic research of the inbred rat.

About this research paper

What this paper is about

In the experiment ,It were selected that 20 primers were assigned on 7 chromosomes of inbred rat.DNA polymorphism of 8 colonies from 6 inbred rat strains(SHR.SHRSP、WKY.LEW.RCS.F344) were studied in national Beijing and Harbin using PCR一analyzed microsatellites .The results indicated that there were remarkable polymorphism in 9 microsatellite loci ;There is apolymorphism among the various rat strains ;and no polymorphism in the same rat strains except SMST locus of SHR(Harbin) and AGT locus of WKY( Harbin) and there is a little difference among the same inbred rat strains in different areas . The method of PCR 一analyzed microsatellites can be used for distinguishing between inbred and outbred .different strains .strain and substrain .and it provides a lot of information for genetic mapping ,gene location and heredity probe of the inbred rat strains ,and a speedy.conve-nient method for genetic research of the inbred rat.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

In the experiment ,It were selected that 20 primers were assigned on 7 chromosomes of inbred rat.DNA polymorphism of 8 colonies from 6 inbred rat strains(SHR.SHRSP、WKY.LEW.RCS.F344) were studied in national Beijing and Harbin using PCR一analyzed microsatellites .The results indicated that there were remarkable polymorphism in 9 microsatellite loci ;There is apolymorphism among the various rat strains ;and no polymorphism in the same rat strains except SMST locus of SHR(Harbin) and AGT locus of WKY( Harbin) and there is a little difference among the same inbred rat strains in different areas . The method of PCR 一analyzed microsatellites can be used for distinguishing between inbred and outbred .different strains .strain and substrain .and it provides a lot of information for genetic mapping ,gene location and heredity probe of the inbred rat strains ,and a speedy.conve-nient method for genetic research of the inbred rat.

Key concepts: Inbred strain, Biology, Microsatellite, Locus (genetics), Genetics, Genetic monitoring, Gene, Polymorphism (computer science)

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Rat Gene Polymorphism Using PC R一Analyzed Microsatellites — Research Paper | ScholarLens