Comparison of different tidal volume of volume-controlled ventilation during one-lung ventilation for esophageal cancer radical operation

Objective To compare the impacts of different tidal volume of volume-controlled ventilation(VCV) on hemodynamic state,airway pressures,and arterial oxygenation during one-lung ventilation(OLV) for esophageal cancer radical operation.Methods Totally 50 ASA I～Ⅱadult patients undergoing esophageal cancer radical operation,were randomized equally into 2 groups:group A(low tidal volume with high respiratory rate) and group B(normal tidal volume with normal respiratory rate) .after anesthetic induction,the patients received two-lung ventilation followed by one-long ventilation.During one-long ventilation,the patients of group A received tidal volume 6ml/kg and respiratory rate 18/min,the patients of group B received tidal volume 10ml/kg and respiratory rate 12/min.Hemodynamics,peak airway pressure(Ppeak) ,PaO2,and were determined at different time points in both groups.Results Hemodynamic indices did not differ significantly between the two groups(P0.05) .the Ppeak of group A was lower than that of group B significantly(P0.05) ,the PaO2 of group A was higher than that of group B significantly(P0.05) .Conclusions During OLV for esophageal cancer radical operation,low tidal volume with high respiratory rate is superior to normal tidal volume with normal respiratory rate in lowering airway pressure and increasing PaO2.